CEN ISO/TS 12025:2015

SLOVENSKI STANDARD
01-julij-2015
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DHURVROD,6276
Nanomaterials - Quantification of nano-object release from powders by generation of
aerosols (ISO/TS 12025:2012)
Nanomaterialien - Quantifizierung der Freisetzung von Nanoobjekten aus Pulvern durch
Aerosolerzeugung (ISO/TS 12025:2012)
Nanomatériaux - Quantification de la libération de nano-objets par les poudres par
production d'aérosols (ISO/TS 12025:2012)
Ta slovenski standard je istoveten z: CEN ISO/TS 12025:2015
ICS:
07.120 Nanotehnologije Nanotechnologies
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

TECHNICAL SPECIFICATION
CEN ISO/TS 12025
SPÉCIFICATION TECHNIQUE
TECHNISCHE SPEZIFIKATION
May 2015
ICS 07.030
English Version
Nanomaterials - Quantification of nano-object release from
powders by generation of aerosols (ISO/TS 12025:2012)
Nanomatériaux - Quantification de la libération de nano- Nanomaterialien - Quantifizierung der Freisetzung von
objets par les poudres par production d'aérosols (ISO/TS Nanoobjekten aus Pulvern durch Aerosolerzeugung
12025:2012) (ISO/TS 12025:2012)
This Technical Specification (CEN/TS) was approved by CEN on 16 May 2015 for provisional application.

The period of validity of this CEN/TS is limited initially to three years. After two years the members of CEN will be requested to submit their
comments, particularly on the question whether the CEN/TS can be converted into a European Standard.

CEN members are required to announce the existence of this CEN/TS in the same way as for an EN and to make the CEN/TS available
promptly at national level in an appropriate form. It is permissible to keep conflicting national standards in force (in parallel to the CEN/TS)
until the final decision about the possible conversion of the CEN/TS into an EN is reached.

CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia,
Finland, Former Yugoslav Republic of Macedonia, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania,
Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey and United
Kingdom.
EUROPEAN COMMITTEE FOR STANDARDIZATION
COMITÉ EUROPÉEN DE NORMALISATION

EUROPÄISCHES KOMITEE FÜR NORMUNG

CEN-CENELEC Management Centre: Avenue Marnix 17, B-1000 Brussels
© 2015 CEN All rights of exploitation in any form and by any means reserved Ref. No. CEN ISO/TS 12025:2015 E
worldwide for CEN national Members.

Contents
Page
Foreword .3

Foreword
The text of ISO/TS 12025:2012 has been prepared by Technical Committee ISO/TC 229 “Nanotechnologies”
of the International Organization for Standardization (ISO) and has been taken over as
held by AFNOR.
Attention is drawn to the possibility that some of the elements of this document may be the subject of patent
rights. CEN [and/or CENELEC] shall not be held responsible for identifying any or all such patent rights.
According to the CEN-CENELEC Internal Regulations, the national standards organizations of the following
countries are bound to announce this Technical Specification: Austria, Belgium, Bulgaria, Croatia, Cyprus,
Czech Republic, Denmark, Estonia, Finland, Former Yugoslav Republic of Macedonia, France, Germany,
Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland,
Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey and the United Kingdom.
Endorsement notice
The text of ISO/TS 12025:2012 has been approved by CEN as CEN ISO/TS 12025:2015 without any
modification.
TECHNICAL ISO/TS
SPECIFICATION 12025
First edition
2012-11-01
Nanomaterials — Quantification of
nano-object release from powders by
generation of aerosols
Nanomatériaux — Quantification de la libération de nano-objets par
les poudres par production d’aérosols
Reference number
ISO/TS 12025:2012(E)
©
ISO 2012
ISO/TS 12025:2012(E)
© ISO 2012
All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized in any form or by any
means, electronic or mechanical, including photocopying and microfilm, without permission in writing from either ISO at the
address below or ISO’s member body in the country of the requester.
ISO copyright office
Case postale 56 • CH-1211 Geneva 20
Tel. + 41 22 749 01 11
Fax + 41 22 749 09 47
E-mail copyright@iso.org
Web www.iso.org
Published in Switzerland
ii © ISO 2012 – All rights reserved

ISO/TS 12025:2012(E)
Contents Page
Foreword .iv
Introduction .v
1  Scope . 1
2  Normative references . 1
3  Terms, definitions and abbreviated terms . 1
3.1 General terms . 1
3.2 Terms related to particle properties and measurement . 2
4  Symbols . 4
5  Factors influencing results of nano-object release from powders .5
5.1 Test method selection . 5
5.2 Material properties influencing nano-object release from powder . 5
5.3 Test stages . 6
6 Test requirements . 7
6.1 General . 7
6.2 Safety assessment . 7
6.3 Sample preparation . 8
6.4 Sample treatment . 8
6.5 Measurement of aerosolized nano-objects .10
7  Requirements for test setups and protocols .14
8  Data reporting .15
Annex A (informative) Considerations for the selection of the treatment procedure .16
Annex B (informative) Rotating drum and continuous drop methods .18
Annex C (informative) Vortex shaker method .21
Annex D (informative) Dynamic method .23
Annex E (informative) Disagglomeration principles .26
Annex F (informative) Selection of the nano-object measuring method .27
Bibliography .30
ISO/TS 12025:2012(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
International Standards are drafted in accordance with the rules given in the ISO/IEC Directives, Part 2.
The main task of technical committees is to prepare International Standards. Draft International
Standards adopted by the technical committees are circulated to the member bodies for voting.
Publication as an International Standard requires approval by at least 75 % of the member bodies
casting a vote.
In other circumstances, particularly when there is an urgent market requirement for such documents, a
technical committee may decide to publish other types of document:
— an ISO Publicly Available Specification (ISO/PAS) represents an agreement between technical
experts in an ISO working group and is accepted for publication if it is approved by more than 50 %
of the members of the parent committee casting a vote;
— an ISO Technical Specification (ISO/TS) represents an agreement between the members of a
technical committee and is accepted for publication if it is approved by 2/3 of the members of the
committee casting a vote.
An ISO/PAS or ISO/TS is reviewed after three years in order to decide whether it will be confirmed for
a further three years, revised to become an International Standard, or withdrawn. If the ISO/PAS or
ISO/TS is confirmed, it is reviewed again after a further three years, at which time it must either be
transformed into an International Standard or be withdrawn.
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights.
ISO/TS 12025 was prepared by Technical Committee ISO/TC 229, Nanotechnologies.
iv © ISO 2012 – All rights reserved

ISO/TS 12025:2012(E)
Introduction
The emissions or release of nano-objects into the surrounding air from powdered nanostructured
materials resulting from handling is an important consideration in the design and operation of many
industrial processes. Released nano-objects may affect human health and the environment, depending
on the nature and quanitity of the nanomaterial. It is therefore important to obtain data about the
propensity of nanomaterials to release nano-objects, thereby allowing exposure to be evaluated,
controlled and minimised.
Three main target groups of experts for the evaluation of the release of nano-objects from powdered
nanostructured materials are:
— material scientists and engineers, who design safe nanomaterials and safe nanomaterial
handling processes;
— occupational, health and safety specialists;
— environmental specialists, who need exposure data in addition to toxicity data for risk assessment
of manufactured nanomaterials (see A.2) and who collect dustiness data (gravimetric as well as
particle concentration and particle size information).
The propensity of nanomaterials to release nano-objects into the air is determined by test methods
devised to apply energy to a sample to stress the intra-particle bonds. This stressing induces abrasion,
erosion or comminution, which causes dissemination of the particles into the gaseous phase,
...