Standard Practice for Identification of Seized Drugs

SIGNIFICANCE AND USE
4.1 These are minimum requirements applicable to the identification of seized drugs.  
4.1.1 As these are minimum requirements, it should be recognized that they may not be sufficient for the identification of all drugs in all circumstances. Within these requirements, it is the responsibility of the individual laboratory’s management to determine which combination of analytical techniques best satisfies the requirements of its jurisdiction.4  
4.2 Correct identification of a drug or chemical depends on the competence of the analyst and the use of an analytical scheme that incorporates validated methods (see Practice E2549). It is expected that in the absence of unforeseen error, an appropriate analytical scheme effectively results in reliable and scientifically supported identifications5 (see Practice E2764).  
4.3 This practice requires the laboratory’s analytical scheme to incorporate techniques that operate on significantly different principles. It does not discourage the use of any particular method within an analytical scheme. Actual practices followed by a particular laboratory may depend upon jurisdictional requirements.
SCOPE
1.1 This practice describes minimum criteria for the qualitative analysis (identification) of seized drugs.  
1.2 Listed are a number of analytical techniques for the identification of seized drugs. These techniques are grouped on the basis of their discriminating power. Analytical schemes based on these groupings are described.  
1.3 Additional information is found in Guides E1968, E1969, E2125, and E2548 and Practices E2326, E2327, E2549, and E2764.  
1.4 This standard should be used in conjunction with sound professional judgment, and cannot replace knowledge, skill, or ability acquired through appropriate education, training, and experience.  
1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.  
1.6 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

General Information

Status
Published
Publication Date
30-Sep-2017
Technical Committee
E30 - Forensic Sciences
Drafting Committee
E30.01 - Criminalistics

Relations

Effective Date
01-May-2015
Effective Date
01-Sep-2011
Effective Date
01-Sep-2011
Effective Date
01-Jun-2011
Effective Date
01-Mar-2011
Effective Date
01-Mar-2011
Effective Date
01-Mar-2011
Effective Date
15-Dec-2010
Effective Date
01-Aug-2009
Effective Date
01-Apr-2009
Effective Date
01-Mar-2007
Effective Date
01-Mar-2007
Effective Date
01-Aug-2006
Effective Date
01-Oct-2004
Effective Date
01-Jul-2004

Overview

ASTM E2329-17: Standard Practice for Identification of Seized Drugs sets out the minimum requirements for the qualitative analysis of seized drugs within forensic laboratories. Developed by ASTM International, this standard helps ensure consistency, quality, and reliability in drug identification processes across jurisdictions. It is widely referenced in forensic science for the qualitative identification of substances, supporting both legal proceedings and regulatory compliance.

The standard emphasizes the use of validated analytical techniques and professional judgment, ensuring that identifications are reliable and scientifically defensible. While it establishes baseline criteria, individual laboratories retain discretion to choose combinations of methods that best comply with jurisdictional and case-specific requirements.

Key Topics

ASTM E2329-17 addresses several critical aspects of seized drug identification, including:

  • Minimum Requirements: Sets out the foundational requirements that laboratories must meet, but recognizes these may not be sufficient for all situations.
  • Analytical Techniques: Categorizes analytical methods by their discriminating power:
    • Category A: High-specificity techniques (e.g., infrared spectroscopy, mass spectrometry, nuclear magnetic resonance).
    • Category B: Techniques with moderate specificity (e.g., capillary electrophoresis, gas chromatography, liquid chromatography).
    • Category C: Tests with lower specificity (e.g., color tests, immunoassays, melting point).
  • Combination of Techniques: Requires the use of at least two uncorrelated techniques, or three methods if high-specificity techniques are not available, to reduce the risk of false positives and negatives.
  • Jurisdictional Flexibility: Laboratories must determine appropriate techniques based on local requirements and available resources.
  • Professional Judgment: The standard does not replace the expertise or training of analysts, emphasizing the crucial role of competency and experience.
  • Data Review: All identifications, especially those using advanced techniques, must be supported with reviewable data such as spectra, chromatograms, or photographs.
  • Quality Assurance: Laboratories must implement quality checks, including sample tracking and the use of controls, to validate results.
  • Safety and Compliance: Users must establish and observe appropriate safety, health, and environmental procedures.

Applications

ASTM E2329-17 is primarily applied in:

  • Forensic Laboratories: Reliable identification of controlled substances and unknown materials seized in law enforcement actions.
  • Legal Proceedings: Ensuring that analytical results presented in court are based on scientifically validated procedures.
  • Quality Assurance Programs: Supporting laboratory accreditation and internal quality management systems.
  • Customs and Border Control: Identifying illicit or suspicious substances in import/export operations.
  • Training: Providing a framework for the education and ongoing training of forensic analysts.

Related Standards

This standard is closely linked to several other ASTM and international guidelines, which together form a comprehensive structure for forensic drug analysis. Key related standards include:

  • ASTM E1968, E1969, E2125: Guides for microcrystal testing of specific drugs.
  • ASTM E2326: Practice for education and training of seized-drug analysts.
  • ASTM E2327: Practice for quality assurance in laboratories performing seized-drug analysis.
  • ASTM E2548: Guide for sampling seized drugs.
  • ASTM E2549: Practice for validation of seized-drug analytical methods.
  • ASTM E2764: Practice for uncertainty assessment in seized-drug analysis.
  • SWGDRUG Recommendations: Provides further guidance for methods, education, and quality assurance in seized drug analysis.

ASTM E2329-17 helps ensure the scientific integrity of forensic drug identification, supporting accurate, defensible results in diverse operational settings and playing a critical role in public safety, regulatory compliance, and the administration of justice.

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Frequently Asked Questions

ASTM E2329-17 is a standard published by ASTM International. Its full title is "Standard Practice for Identification of Seized Drugs". This standard covers: SIGNIFICANCE AND USE 4.1 These are minimum requirements applicable to the identification of seized drugs. 4.1.1 As these are minimum requirements, it should be recognized that they may not be sufficient for the identification of all drugs in all circumstances. Within these requirements, it is the responsibility of the individual laboratory’s management to determine which combination of analytical techniques best satisfies the requirements of its jurisdiction.4 4.2 Correct identification of a drug or chemical depends on the competence of the analyst and the use of an analytical scheme that incorporates validated methods (see Practice E2549). It is expected that in the absence of unforeseen error, an appropriate analytical scheme effectively results in reliable and scientifically supported identifications5 (see Practice E2764). 4.3 This practice requires the laboratory’s analytical scheme to incorporate techniques that operate on significantly different principles. It does not discourage the use of any particular method within an analytical scheme. Actual practices followed by a particular laboratory may depend upon jurisdictional requirements. SCOPE 1.1 This practice describes minimum criteria for the qualitative analysis (identification) of seized drugs. 1.2 Listed are a number of analytical techniques for the identification of seized drugs. These techniques are grouped on the basis of their discriminating power. Analytical schemes based on these groupings are described. 1.3 Additional information is found in Guides E1968, E1969, E2125, and E2548 and Practices E2326, E2327, E2549, and E2764. 1.4 This standard should be used in conjunction with sound professional judgment, and cannot replace knowledge, skill, or ability acquired through appropriate education, training, and experience. 1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.6 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

SIGNIFICANCE AND USE 4.1 These are minimum requirements applicable to the identification of seized drugs. 4.1.1 As these are minimum requirements, it should be recognized that they may not be sufficient for the identification of all drugs in all circumstances. Within these requirements, it is the responsibility of the individual laboratory’s management to determine which combination of analytical techniques best satisfies the requirements of its jurisdiction.4 4.2 Correct identification of a drug or chemical depends on the competence of the analyst and the use of an analytical scheme that incorporates validated methods (see Practice E2549). It is expected that in the absence of unforeseen error, an appropriate analytical scheme effectively results in reliable and scientifically supported identifications5 (see Practice E2764). 4.3 This practice requires the laboratory’s analytical scheme to incorporate techniques that operate on significantly different principles. It does not discourage the use of any particular method within an analytical scheme. Actual practices followed by a particular laboratory may depend upon jurisdictional requirements. SCOPE 1.1 This practice describes minimum criteria for the qualitative analysis (identification) of seized drugs. 1.2 Listed are a number of analytical techniques for the identification of seized drugs. These techniques are grouped on the basis of their discriminating power. Analytical schemes based on these groupings are described. 1.3 Additional information is found in Guides E1968, E1969, E2125, and E2548 and Practices E2326, E2327, E2549, and E2764. 1.4 This standard should be used in conjunction with sound professional judgment, and cannot replace knowledge, skill, or ability acquired through appropriate education, training, and experience. 1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. 1.6 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

ASTM E2329-17 is classified under the following ICS (International Classification for Standards) categories: 11.120.10 - Medicaments. The ICS classification helps identify the subject area and facilitates finding related standards.

ASTM E2329-17 has the following relationships with other standards: It is inter standard links to ASTM E2327-15, ASTM E2548-11e1, ASTM E2548-11, ASTM E2764-11, ASTM E1968-11, ASTM E1969-11, ASTM E2125-11, ASTM E2327-10, ASTM E2326-09, ASTM E2549-09, ASTM E2548-07, ASTM E2125-07, ASTM E1969-06, ASTM E2327-04, ASTM E2326-04. Understanding these relationships helps ensure you are using the most current and applicable version of the standard.

ASTM E2329-17 is available in PDF format for immediate download after purchase. The document can be added to your cart and obtained through the secure checkout process. Digital delivery ensures instant access to the complete standard document.

Standards Content (Sample)


This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the
Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.
Designation: E2329 −17 An American National Standard
Standard Practice for
Identification of Seized Drugs
This standard is issued under the fixed designation E2329; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope E2326 Practice for Education and Training of Seized-Drug
Analysts
1.1 This practice describes minimum criteria for the quali-
E2327 Practice for Quality Assurance of Laboratories Per-
tative analysis (identification) of seized drugs.
forming Seized-Drug Analysis
1.2 Listed are a number of analytical techniques for the
E2548 Guide for Sampling Seized Drugs for Qualitative and
identification of seized drugs.These techniques are grouped on
Quantitative Analysis
the basis of their discriminating power. Analytical schemes
E2549 Practice for Validation of Seized-Drug Analytical
based on these groupings are described.
Methods
1.3 Additional information is found in Guides E1968, E2764 PracticeforUncertaintyAssessmentintheContextof
Seized-Drug Analysis (Withdrawn 2020)
E1969,E2125,andE2548andPracticesE2326,E2327,E2549,
and E2764. 2.2 Other Document:
SWGDRUG Scientific Working Group for the Analysis of
1.4 This standard should be used in conjunction with sound
Seized Drugs—Recommendations for: Education and
professional judgment, and cannot replace knowledge, skill, or
Training, Quality Assurance, Methods of Analysis
ability acquired through appropriate education, training, and
experience.
3. Terminology
1.5 This standard does not purport to address all of the
3.1 Definitions—Terms that may assist in interpreting this
safety concerns, if any, associated with its use. It is the
practice are found in the SWGDRUG Glossary of Terms and
responsibility of the user of this standard to establish appro- 4
Definitions, Annex A.
priate safety, health, and environmental practices and deter-
mine the applicability of regulatory limitations prior to use.
4. Significance and Use
1.6 This international standard was developed in accor-
4.1 These are minimum requirements applicable to the
dance with internationally recognized principles on standard-
identification of seized drugs.
ization established in the Decision on Principles for the
4.1.1 As these are minimum requirements, it should be
Development of International Standards, Guides and Recom-
recognized that they may not be sufficient for the identification
mendations issued by the World Trade Organization Technical
of all drugs in all circumstances. Within these requirements, it
Barriers to Trade (TBT) Committee.
is the responsibility of the individual laboratory’s management
to determine which combination of analytical techniques best
2. Referenced Documents
satisfies the requirements of its jurisdiction.
2.1 ASTM Standards:
4.2 Correct identification of a drug or chemical depends on
E1968 Practice for Microcrystal Testing in Forensic Analy-
the competence of the analyst and the use of an analytical
sis for Cocaine
scheme that incorporates validated methods (see Practice
E1969 Practice for Microcrystal Testing in Forensic Analy-
E2549). It is expected that in the absence of unforeseen error,
sis for Methamphetamine and Amphetamine
an appropriate analytical scheme effectively results in reliable
E2125 Practice for Microcrystal Testing in Forensic Analy-
and scientifically supported identifications (see Practice
sis for Phencyclidine and Its Analogues
E2764).
This practice is under the jurisdiction of ASTM Committee E30 on Forensic
Sciences and is the direct responsibility of Subcommittee E30.01 on Criminalistics. The last approved version of this historical standard is referenced on
Current edition approved Oct. 1, 2017. Published October 2017. Originally www.astm.org.
approved in 2004. Last previous edition approved in 2014 as E2329 – 14. DOI: Available from the Scientific Working Group for theAnalysis of Seized Drugs
10.1520/E2329-17. (SWGDRUG), http://www.swgdrug.org/approved.htm.
2 5
For referenced ASTM standards, visit the ASTM website, www.astm.org, or EURACHEM, The Fitness for Purpose of Analytical Methods – A Laboratory
contact ASTM Customer Service at service@astm.org. For Annual Book of ASTM Guide to Method Validation and Related Topics, 2nd ed., 2014.
Standards volume information, refer to the standard’s Document Summary page on Milman, B. L., Chemical Identification and Its Quality Assurance, Springer-
the ASTM website. Verlag, 2011.
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
E2329 − 17
4.3 This practice requires the laboratory’s analytical scheme 6.1.3 Identification of botanical material may alternatively
to incorporate techniques that operate on significantly different be made utilizing morphological characteristics (Category B)
principles. It does not discourage the use of any particular
alone provided sufficient botanical features appropriate for
method within an analytical scheme.Actual practices followed identification are observed. Such examinations shall only be
by a particular laboratory may depend upon jurisdictional
made by analysts competent in botanical identifications. In this
requirements.
context, botanical competence exclusively applies to those
examiners recognized as professional botanists or those as-
5. Categories of Analytical Techniques
sessed to be competent by such. Identifications of chemical
5.1 For the purpose of this practice, techniques for the components contained in botanicals (mescaline, opiates,
psilocin, etc.) should rely on principles of chemical identifica-
analysis of drug sam
...


This document is not an ASTM standard and is intended only to provide the user of an ASTM standard an indication of what changes have been made to the previous version. Because
it may not be technically possible to adequately depict all changes accurately, ASTM recommends that users consult prior editions as appropriate. In all cases only the current version
of the standard as published by ASTM is to be considered the official document.
Designation: E2329 − 14 E2329 − 17
Standard Practice for
Identification of Seized Drugs
This standard is issued under the fixed designation E2329; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope
1.1 This practice describes minimum criteria for the qualitative analysis (identification) of seized drugs.
1.2 Listed are a number of analytical techniques for the identification of seized drugs. These techniques are grouped on the basis
of their discriminating power. Analytical schemes based on these groupings are described.
1.3 Additional information is found in Guides E1968, E1969, E2125, and E2548 and Practices E2326, E2327, E2549, and
E2764.
1.4 This practice does not replace knowledge, skill, ability, experience, education or training and should be used in conjunction
with professional judgment.standard should be used in conjunction with sound professional judgment, and cannot replace
knowledge, skill, or ability acquired through appropriate education, training, and experience.
1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility
of the user of this standard to establish appropriate safety safety, health, and healthenvironmental practices and determine the
applicability of regulatory limitations prior to use.
1.6 This international standard was developed in accordance with internationally recognized principles on standardization
established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued
by the World Trade Organization Technical Barriers to Trade (TBT) Committee.
2. Referenced Documents
2.1 ASTM Standards:
E1968 Guide for Microcrystal Testing in Forensic Analysis of Cocaine
E1969 Guide for Microcrystal Testing in Forensic Analysis of Methamphetamine and Amphetamine
E2125 Guide for Microcrystal Testing in Forensic Analysis of Phencyclidine and Its Analogues
E2326 Practice for Education and Training of Seized-Drug Analysts
E2327 Practice for Quality Assurance of Laboratories Performing Seized-Drug Analysis
E2548 Guide for Sampling Seized Drugs for Qualitative and Quantitative Analysis
E2549 Practice for Validation of Seized-Drug Analytical Methods
E2764 Practice for Uncertainty Assessment in the Context of Seized-Drug Analysis
2.2 Other Document:
SWGDRUG Scientific Working Group for the Analysis of Seized Drugs—Recommendations for: Education and Training,
Quality Assurance, Methods of Analysis
3. Terminology
3.1 Definitions—Terms that may assist in interpreting this practice are found in the SWGDRUG glossary.Glossary of Terms and
Definitions, Annex A.
4. Significance and Use
4.1 These are minimum requirements applicable to the identification of seized drugs.
This practice is under the jurisdiction of ASTM Committee E30 on Forensic Sciences and is the direct responsibility of Subcommittee E30.01 on Criminalistics.
Current edition approved Dec. 1, 2014Oct. 1, 2017. Published December 2014October 2017. Originally approved in 2004. Last previous edition approved in 20102014
as E2329 – 10.E2329 – 14. DOI: 10.1520/E2329-14.10.1520/E2329-17.
For referenced ASTM standards, visit the ASTM website, www.astm.org, or contact ASTM Customer Service at service@astm.org. For Annual Book of ASTM Standards
volume information, refer to the standard’s Document Summary page on the ASTM website.
Available from the Scientific Working Group for the Analysis of Seized Drugs (SWGDRUG), http://www.swgdrug.org.http://www.swgdrug.org/approved.htm.
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
E2329 − 17
4.1.1 As these are minimum requirements, it should be recognized that they may not be sufficient for the identification of all
drugs in all circumstances. Within these requirements, it is up to the the responsibility of the individual laboratory’s management
to determine which combination of analytical techniques best satisfies the requirements of its jurisdiction.
4.2 Correct identification of a drug or chemical depends on the competence of the analyst and the use of an analytical scheme
based onthat incorporates validated methods (see Practice E2549) and the competence of the analyst. ). It is expected that in the
absence of unforeseen error, an appropriate analytical scheme effectively results in no uncertainty in reportedreliable and
scientifically supported identifications (see Practice E2764).
4.3 This practice requires the use of multiple uncorrelated techniques. laboratory’s analytical scheme to incorporate techniques
that operate on significantly different principles. It does not discourage the use of any particular method within an analytical
scheme. Unique requirements in different jurisdictions may dictate the actual Actual practices followed by a particular
laboratory.laboratory may depend upon jurisdictional requirements.
5. Categories of Analytical Techniques
5.1 For the purpose of this practice, techniques for the analysis of drug samples are classified into three categories (see Table
1) based on their maximum potential discriminating power. However, the classification of a technique may be lower, if the sample,
analyte, or mode of operation diminishes its discriminating power.
5.1.1 Examples of diminished discriminating power may include:include but are not limited to:
5.1.1.1 An infrared spectroscopy technique applied to a mixture which produces a combined spectrum, and
5.1.1.2 A mass spectrometry technique (low or high resolution) which only produces molecular weight information.
6. Identification Criteria
6.1 This practice requires that the following minimum criteria be utilized when making analytical identifications:
6.1.1 When a validated Category A technique is incorporated into an analyti
...

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