SIST EN ISO 23196:2024
(Main)Water quality - Calculation of biological equivalence (BEQ) concentrations (ISO 23196:2022)
Water quality - Calculation of biological equivalence (BEQ) concentrations (ISO 23196:2022)
This document specifies the derivation of biological equivalence (BEQ) concentrations for results of in vitro bioassays which are based on measuring effects on a biological process such as enzyme induction or cellular growth. The concept described here can be used for any biological assay after the proof of its applicability.
To derive BEQ concentrations, the effect on a biological process caused by a sample – i.e. the activity of the sample – is expressed in terms of a concentration of a reference compound which results in an equivalent effect on the process. The term "sample" used in this document addresses environmental samples as well as defined mixtures and pure compounds used as test item in a bioassay. BEQ concentrations can be derived for environmental water samples, extracts of environmental water samples including tap water or solutions of pure chemicals or mixtures of chemicals.
Wasserbeschaffenheit - Berechnung biologischer Äquivalenzkonzentrationen (BEQ) (ISO 23196:2022)
Dieses Dokument legt die Ableitung von biologischen Äquivalenzkonzentrationen (BEQ) für Ergebnisse von in-vitro-Bioassays fest, die auf der Messung von Effekten auf biologische Prozesse wie eine Enzyminduktion oder Zellwachstum beruhen. Das hier beschriebene Konzept kann nach dem Nachweis seiner Anwendbarkeit für jeden biologischen Assay verwendet werden.
Zur Ableitung einer BEQ-Konzentration wird der durch eine Probe verursachte Effekt auf einen biologischen Prozess – d. h. die Aktivität der Probe – als Konzentration einer Referenzverbindung ausgedrückt, die einen gleichen Effekt hervorruft. Der in diesem Dokument verwendete Begriff „Probe“ bezieht sich sowohl auf Umweltproben als auch auf definierte Gemische und reine Verbindungen, die als Prüfgegenstand in einem Bioassay verwendet werden. BEQ-Konzentrationen können für wässrige Umweltproben, Extrakte von wässrigen Umweltproben einschließlich Leitungswasser oder Lösungen von reinen Chemikalien oder Chemikaliengemischen abgeleitet werden.
Qualité de l'eau - Calcul des concentrations en équivalent biologique (BEQ) (ISO 23196:2022)
Le présent document spécifie la détermination de concentrations en équivalent biologique (BEQ) à partir de résultats de bioessais in vitro qui sont fondés sur la mesure des effets produits sur un processus biologique tel que l’induction d’enzymes ou la croissance cellulaire. Le concept décrit ici peut être utilisé pour n’importe quel bioessai du moment que son applicabilité a été démontrée.
Pour déterminer les concentrations BEQ, l’effet produit par un échantillon sur un processus biologique, c’est-à-dire l’activité de l’échantillon, est exprimé sous la forme de la concentration d’un composé de référence à laquelle un effet équivalent est obtenu sur le processus. Le terme «échantillon» utilisé dans le présent document renvoie à des échantillons environnementaux ainsi qu’à des mélanges déterminés et à des composés purs utilisés comme objets de mesure dans le cadre d’un bioessai. Les concentrations en équivalent biologique peuvent être déterminées pour des échantillons d’eau environnementaux, des extraits d’échantillons d’eau environnementaux, y compris d’eau du robinet, ou des solutions de substances chimiques pures ou de mélanges de substances chimiques.
Kakovost vode - Izračun biološko ekvivalentnih koncentracij (BEQ) (ISO 23196:2022)
Ta dokument določa izpeljavo biološko ekvivalentnih koncentracij (BEQ) za rezultate bioloških preskusov in vitro, ki temeljijo na merjenju učinkov bioloških procesov, kot je indukcija encimov ali celična rast. Koncept, opisan v tem dokumentu, je mogoče uporabiti za kateri koli biološki preskus z dokazano uporabnostjo.
Za izpeljavo biološko ekvivalentnih koncentracij (BEQ) je učinek biološkega procesa, ki ga sproži vzorec – tj. aktivnost vzorca – izražen kot koncentracija referenčne spojine, ki je posledica enakovrednega učinka na proces. Izraz »vzorec« se v tem dokumentu nanaša na okoljske vzorce in opredeljene mešanice in čiste spojine, ki se uporabljajo kot preskušanec v biološkem preskusu. Biološko ekvivalente koncentracije je mogoče izpeljati iz vzorcev vode iz okolja, ekstraktov vzorcev vode iz okolja, vključno z vodo iz pipe ali raztopin čistih kemikalij ali mešanice kemikalij.
General Information
Standards Content (Sample)
SLOVENSKI STANDARD
SIST EN ISO 23196:2024
01-februar-2024
Kakovost vode - Izračun biološko ekvivalentnih koncentracij (BEQ) (ISO
23196:2022)
Water quality - Calculation of biological equivalence (BEQ) concentrations (ISO
23196:2022)
Wasserbeschaffenheit - Berechnung biologischer Äquivalenzkonzentrationen (BEQ)
(ISO 23196:2022)
Qualité de l'eau - Calcul des concentrations en équivalent biologique (BEQ) (ISO
23196:2022)
Ta slovenski standard je istoveten z: EN ISO 23196:2023
ICS:
13.060.70 Preiskava bioloških lastnosti Examination of biological
vode properties of water
SIST EN ISO 23196:2024 en,fr,de
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.
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SIST EN ISO 23196:2024
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SIST EN ISO 23196:2024
EN ISO 23196
EUROPEAN STANDARD
NORME EUROPÉENNE
August 2023
EUROPÄISCHE NORM
ICS 13.060.70
English Version
Water quality - Calculation of biological equivalence (BEQ)
concentrations (ISO 23196:2022)
Qualité de l'eau - Calcul des concentrations en Wasserbeschaffenheit - Berechnung biologischer
équivalent biologique (BEQ) (ISO 23196:2022) Äquivalenzkonzentrationen (BEQ) (ISO 23196:2022)
This European Standard was approved by CEN on 21 August 2023.
CEN members are bound to comply with the CEN/CENELEC Internal Regulations which stipulate the conditions for giving this
European Standard the status of a national standard without any alteration. Up-to-date lists and bibliographical references
concerning such national standards may be obtained on application to the CEN-CENELEC Management Centre or to any CEN
member.
This European Standard exists in three official versions (English, French, German). A version in any other language made by
translation under the responsibility of a CEN member into its own language and notified to the CEN-CENELEC Management
Centre has the same status as the official versions.
CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia,
Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway,
Poland, Portugal, Republic of North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Türkiye and
United Kingdom.
EUROPEAN COMMITTEE FOR STANDARDIZATION
COMITÉ EUROPÉEN DE NORMALISATION
EUROPÄISCHES KOMITEE FÜR NORMUNG
CEN-CENELEC Management Centre: Rue de la Science 23, B-1040 Brussels
© 2023 CEN All rights of exploitation in any form and by any means reserved Ref. No. EN ISO 23196:2023 E
worldwide for CEN national Members.
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SIST EN ISO 23196:2024
EN ISO 23196:2023 (E)
Contents Page
European foreword . 3
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SIST EN ISO 23196:2024
EN ISO 23196:2023 (E)
European foreword
The text of ISO 23196:2022 has been prepared by Technical Committee ISO/TC 147 "Water quality” of
the International Organization for Standardization (ISO) and has been taken over as EN ISO 23196:2023
by Technical Committee CEN/TC 230 “Water analysis” the secretariat of which is held by DIN.
This European Standard shall be given the status of a national standard, either by publication of an
identical text or by endorsement, at the latest by February 2024, and conflicting national standards
shall be withdrawn at the latest by February 2024.
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. CEN shall not be held responsible for identifying any or all such patent rights.
Any feedback and questions on this document should be directed to the users’ national standards body.
A complete listing of these bodies can be found on the CEN website.
According to the CEN-CENELEC Internal Regulations, the national standards organizations of the
following countries are bound to implement this European Standard: Austria, Belgium, Bulgaria,
Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland,
Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Republic of
North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Türkiye and the
United Kingdom.
Endorsement notice
The text of ISO 23196:2022 has been approved by CEN as EN ISO 23196:2023 without any modification.
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SIST EN ISO 23196:2024
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SIST EN ISO 23196:2024
INTERNATIONAL ISO
STANDARD 23196
First edition
2022-02
Water quality — Ca
...
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