ISO 17190-2:2021

INTERNATIONAL ISO
STANDARD 17190-2
Second edition
Urine-absorbing aids for
incontinence — Polyacrylate
superabsorbent powders —
Part 2:
Test method for determination of
the amount of residual acrylate
monomers
Aides pour absorption d'urine — Méthodes d'essai pour caractériser
les matériaux absorbants à base de polymères —
Partie 2: Détermination de la quantité de monomères résiduels
PROOF/ÉPREUVE
Reference number
ISO 17190-2:2020(E)
©
ISO 2020

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ISO 17190-2:2020(E)

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© ISO 2020
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
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Published in Switzerland
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ISO 17190-2:2020(E)

Contents Page
Foreword .iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Principle . 2
5 Reagents and materials . 2
5.1 Water. . 2
5.2 Sodium chloride solution. . 2
5.3 Phosphoric acid. . 2
5.4 Phosphoric acid solution. . 2
5.5 Acetonitrile. . 2
5.6 Acrylic acid. . 2
6 Apparatus . 3
7 Calibration . 4
8 Conditioning . 4
9 Sampling . 4
10 Procedure. 5
11 Calculation . 6
11.1 Calibration curve . 6
11.2 Amount of residual monomers . 6
12 Report . 7
13 Precision . 7
Annex A (informative) Notes on chromatographical testing . 8
Bibliography .10
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ISO 17190-2:2020(E)

Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www .iso .org/ directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www .iso .org/ patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to the
World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT) see www .iso .org/
iso/ foreword .html.
This document was prepared by Technical Committee ISO/TC 173, Assistive products, Subcommittee
SC 3, Aids for ostomy and incontinence.
This second edition cancels and replaces the first edition (ISO 17190-2:2001), which has been technically
revised. The main changes compared to the previous edition are as follows:
— full text review and new laboratory analysis with statistical evaluation.
A list of all parts in the ISO 17190 series can be found on the ISO website.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www .iso .org/ members .html.
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INTERNATIONAL STANDARD ISO 17190-2:2020(E)
Urine-absorbing aids for incontinence — Polyacrylate
superabsorbent powders —
Part 2:
Test method for determination of the amount of residual
acrylate monomers
WARNING — This document does not claim to address all of the safety concerns, if any, associated
with its use. It is the responsibility of the user of this document to establish appropriate safety
and health practices and determine the applicability of regulatory limitations prior to use. It
is expected that the person performing this test has been fully trained in all aspects of this
procedure.
1 Scope
This document provides a test method for determining the sum of residual monomeric sodium acrylate
and acrylic acid present in polyacrylate superabsorbent powders as acrylic acid.
2 Normative references
The following documents are referred to in the text in such a way that some or all of their content
constitutes requirements of this document. For dated references, only the edition cited applies. For
undated references, the latest edition of the referenced document (including any amendments) applies.
ISO 187, Paper, board and pulps — Standard atmosphere for conditioning and testing and procedure for
monitoring the atmosphere and conditioning of samples
ISO 3696, Water for analytical laboratory use — Specification and test methods
3 Terms and definitions
For the purposes of this document, the following terms and definitions apply.
ISO and IEC maintain terminological databases for use in standardization at the following addresses:
— ISO Online browsing platform: available at https:// www .iso .org/ obp
— IEC Electropedia: available at http:// www .electropedia .org/
3.1
amount of residual monomers
sum of residual monomeric sodium acrylate and acrylic acid
3.2
sample
product or portion of a product taken from a production lot for testing purposes and identifiable and
traceable back to its origin
3.3
specimen
specific portion of the identified sample (3.2) upon which a test is performed
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ISO 17190-2:2020(E)

4 Principle
Residual monomeric sodium acrylate and acrylic acid are extracted from the polyacrylate
superabsorbent powders and the amount determined as residual acrylate monomer by HPLC.
The method described here uses a simple 1 g in 200 ml dilution factor. However, it is equally valid to
use different masses and volumes as long as the mass: volume dilution ratio is the same and suitable
experimental validation is performed.
5 Reagents and materials
Use only reagents of recognized analytical grade, unless otherwise specified.
5.1 Water.
Grade 1 water according to ISO 3696, for the standard solutions for the calibration and Grade 3 water
according to ISO 3696, with the exception that the conductivity can be as high as 30 μS/cm, for the
saline solution.
5.2 Sodium chloride solution.
5.2.1 0,9 % mass fraction of sodium chloride solution in water. Weigh (9,00 ± 0,01) g of sodium chloride
into a 1 l beaker and add (991,0 ± 0,1) g of deionized water (grade 3). Stir until dissolved.
5.2.2 The conductivity of the solution should be checked prior to each use using properly calibrated
measuring equipment. The expected conductivity of a 0,9 % saline solution is of the order of 1600 S/m
(depending on temperature). Each testing lab shall determine the correct conductivity for the conditions
obtaining in the lab. It is also recommended that the temperature of the solution be maintained at
(23 ± 2) °C for the duration of the test. As this matches the required laboratory temperature it is not
necessary to record the solution temperature.
5.3 Phosphoric acid.
Concentrated c(H P0 ) = 85 % by mass, of HPLC grade or better.
3 4
5.4 Phosphoric acid solution.
c(H PO ) = 0,1 % by mass (1 g/l or 0,0087 mol/l). Dilute concentrated H PO to volume with deionized
3 4 3 4
water (grade 1). Stir until dissolved.
5.5 Acetonitrile.
HPLC grade or better.
5.6 Acrylic acid.
Greater than 99,5 % purity.
Acrylic acid degrades over time owing to slow polymerization, particularly dimerization, and water
uptake. It is important to obtain acrylic acid that meets the purity required for this test method. It is not
recommended to obtain the reference substance from a laboratory chemicals distributor as the purity
of this material from such a source is likely to be defined inaccurately.
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ISO 17190-2:2020(E)

6 Apparatus
6.1 Analytical balance, capable of weighing a mass of (100,000 ± 0,001) g of polymer powder in
combination with the mass of the weighing vessel or laboratory paper employed.
6.2 Analytical balance, capable of weighing a mass of (9,00 ± 0,01) g of sodium chloride in combination
with the mass of the weighing vessel or laboratory paper employed.
6.3 Analytical balance, capable of weighing a mass of (1000,00 ± 1,00) g of sodium chloride solution
in combination with the mass of the vessel
...