ISO/TC 24/SC 4/WG 5 - Liquid displacement methods

This document specifies the measurements of particle size distribution and concentration of suspended particles, ranging from 40 nm to 100 µm, using tunable resistive pulse sensing (TRPS). This document provides a comprehensive overview of the methodologies that are applied to achieve reproducible and accurate TRPS measurement results. This document also includes best practice considerations, possible pitfalls and information on how to alleviate or avoid these pitfalls.

This document specifies the measurement of the size distribution of particles dispersed in an electrolyte solution using the electrical sensing zone method. This can include biologics such as cells, but also industrial particles such as carbon, cement, ceramic powders, metal powders, pigments and polymer powders. The method measures pulse heights and their relationship to particle volumes or diameters, and is applicable over the range (implementation dependant) from approximately 0,5 μm tο above 1 mm. This document does not address the specific requirements of the measurement of specific materials.

ISO 13319:2007 gives guidance on the measurement of the size distribution of particles dispersed in an electrolyte solution using the electrical sensing zone method. The method measures pulse heights and their relationship to particle volumes or diameters, and it reports in the range from approximately 0,4 micrometres to approximately 1 200 micrometres. It does not address the specific requirements of the measurement of specific materials. However, guidance on the measurements of conducting materials such as porous materials and metal powders is given.