ASTM C1379-10
(Test Method)Standard Test Method for Analysis of Urine for Uranium-235 and Uranium-238 Isotopes by Inductively Coupled Plasma-Mass Spectrometry (Withdrawn 2017)
Standard Test Method for Analysis of Urine for Uranium-235 and Uranium-238 Isotopes by Inductively Coupled Plasma-Mass Spectrometry (Withdrawn 2017)
SIGNIFICANCE AND USE
DOE Order 5480.11 and ANSI N13.30 require that internal dose assessments be made as part of the bioassay program for nuclear facility workers. For indirect bioassay of uranium workers, the uranium isotopes must be measured along with the total uranium in urine samples. The RMDA for each uranium isotope is 0.1 pCi/L.
This method is applicable for measuring 235U and 238U at the RMDA. Because of extremely low mass concentration (because of the high specific activity), 234U cannot be measured without additional sample preconcentration.
Note 2—Column chromatography separations and concentration of 234U using manual or flow-injection preconcentration followed by ICP-MS isotopic determination are described in Test Methods C1310 and C1345. These methods focus on environmental soil sample analysis, but with some development, may be applicable to digested urine samples. The 234U concentration can be calculated based on an enrichment gradient for workers in uranium enrichment plants, and internal dose assessments can be made.
Note 3—Use of high resolution ICP-MS may also be used to obtain lower detection limits.
SCOPE
1.1 This test method covers the determination of the concentration of uranium-235 and uranium-238 in urine using Inductively Coupled Plasma-Mass Spectrometry. This test method can be used to support uranium facility bioassay programs.
1.2 This method detection limits for 235U and 238U are 6 ng/L. To meet the requirements of ANSI N13.30, the minimum detectable activity (MDA) of each radionuclide measured must be at least 0.1 pCi/L (0.0037 Bq/L). The MDA translates to 47 ng/L for 235U and 300 ng/L for 238U. Uranium– 234 cannot be determined at the MDA with this test method because of its low mass concentration level equivalent to 0.1 pCi/L.
1.3 The digestion and anion separation of urine may not be necessary when uranium concentrations of more than 100 ng/L are present.
1.4 Units—The values stated in picoCurie per liter units are to be regarded as standard. The values given in parentheses are mathematical conversions to SI units that are provided for information only and are not considered standard.
1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
Note 1—Warning: The ICP-MS is a source of intense ultraviolet radiation from the radio frequency induced plasma. Protection from radio frequency radiation and UV radiation is provided by the instrument under normal operation.
WITHDRAWN RATIONALE
This test method covered the determination of the concentration of uranium-235 and uranium-238 in urine using Inductively Coupled Plasma-Mass Spectrometry. This test method could have been used to support uranium facility bioassay programs.
Formerly under the jurisdiction of Committee C26 on Nuclear Fuel Cycle, this test method was withdrawn in June 2017 and replaced by Test Method C1844 on the Determination of Uranium in Urine by Inductively Coupled Plasma Mass Spectrometer Following Nitric Acid Dilution.1
General Information
Relations
Standards Content (Sample)
NOTICE: This standard has either been superseded and replaced by a new version or withdrawn.
Contact ASTM International (www.astm.org) for the latest information
Designation: C1379 − 10
Standard Test Method for
Analysis of Urine for Uranium-235 and Uranium-238
Isotopes by Inductively Coupled Plasma-Mass
1
Spectrometry
This standard is issued under the fixed designation C1379; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope 2. Referenced Documents
2
1.1 This test method covers the determination of the con- 2.1 ASTM Standards:
centration of uranium-235 and uranium-238 in urine using C859 Terminology Relating to Nuclear Materials
Inductively Coupled Plasma-Mass Spectrometry. This test C1310 Test Method for Determining Radionuclides in Soils
method can be used to support uranium facility bioassay by Inductively Coupled Plasma-Mass Spectrometry Using
3
programs. Flow Injection Preconcentration (Withdrawn 2011)
235 238 C1345 Test Method for Analysis of Total and Isotopic
1.2 This method detection limits for U and U are 6
Uranium and Total Thorium in Soils by Inductively
ng/L.To meet the requirements ofANSI N13.30, the minimum
Coupled Plasma-Mass Spectrometry
detectable activity (MDA) of each radionuclide measured must
D1193 Specification for Reagent Water
be at least 0.1 pCi/L(0.0037 Bq/L). The MDAtranslates to 47
235 238
2.2 Other Documents:
ng/L for U and 300 ng/L for U. Uranium– 234 cannot be
ANSI N13.30 Radiological Measurement Quality
determinedattheMDAwiththistestmethodbecauseofitslow
DOE Order 5480.11 Radiological Measurements Quality
mass concentration level equivalent to 0.1 pCi/L.
3. Terminology
1.3 The digestion and anion separation of urine may not be
necessary when uranium concentrations of more than 100 ng/L
3.1 For terms in this document, see Terminology C859.
are present.
3.2 Definitions:
1.4 Units—The values stated in picoCurie per liter units are
3.2.1 isobar, n—any atom that has the same atomic mass
to be regarded as standard.The values given in parentheses are
number as another atom but a different atomic number.
mathematical conversions to SI units that are provided for
3.3 Acronyms:
information only and are not considered standard.
3.3.1 AMU, n—atomic mass unit
1.5 This standard does not purport to address all of the
3.3.2 CB, n—calibration blank
safety concerns, if any, associated with its use. It is the
3.3.3 COC, n—chain of custody
responsibility of the user of this standard to establish appro-
priate safety and health practices and determine the applica-
3.3.4 CVS, n—calibration verification standard
bility of regulatory limitations prior to use.
3.3.5 ICS, n—instrument check standard
NOTE 1—Warning: The ICP-MS is a source of intense ultraviolet
3.3.6 IDL, n—instrument detection limit
radiation from the radio frequency induced plasma. Protection from radio
3.3.7 LCS, n—laboratory control sample
frequency radiation and UV radiation is provided by the instrument under
normal operation.
3.3.8 MDA, n—minimum detectable activity
1 2
This test method is under the jurisdiction ofASTM Committee C26 on Nuclear For referenced ASTM standards, visit the ASTM website, www.astm.org, or
Fuel Cycle and is the direct responsibility of Subcommittee C26.05 on Methods of contact ASTM Customer Service at service@astm.org. For Annual Book of ASTM
Test. Standardsvolume information, refer to the standard’s Document Summary page on
Current edition approved Jan. 1, 2010. Published February 2010. Originally the ASTM website
3
approved in 1997. Last previous edition approved in 2004 as C1379 – 04. DOI: The last approved version of this historical standard is referenced on
10.1520/C1379-10. www.astm.org.
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
1
---------------------- Page: 1 ----------------------
C1379 − 10
3.3.9 m/e, n—mass/charge ratio 7.2 Appropriate sized disposable graduated test tube with
cap that will accommodate the autosampler.
3.3.10 RMDA, n—required minimum detectable activity
7.3 Twelve-mL disposable polyethylene column or suitable
3.3.11 % RDS, n—percent relative standard deviation—(1
size with frit.
Standard Deviation / Mean) * 100
7.4 Vacuum manifold chamber with regulator valve,
4. Summary of Test Method
vacuum gage, vacuum relief valve, and a vacuum manifold
4.1 A urine sample is digested and wet oxidized with beaker rack (optional).
concentrated nitric and hydrochloric acids to solubilize ura-
nium and to destroy the organic matter. Uranium is selectively
8. Reagents and Materials
separated from the chloride salts by an anion exchange resin
8.1 Purity of Reagents—Reagent grade chemicals shall be
235 238
andiselutedwithdilutenitricacid.The Uand Uisotopes
used in
...
Questions, Comments and Discussion
Ask us and Technical Secretary will try to provide an answer. You can facilitate discussion about the standard in here.