This document provides specifications for the representation of the following types of genomic information: - unaligned sequencing reads including read identifiers and quality values; - aligned sequencing reads including read identifiers and quality values; - reference sequences.

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This document provides specifications for the normative representation of the following types of genomic information: - variants with genotyping information - functional annotations - tracks - expression matrices - contact matrices (from Hi-C experiments or similar).

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This document specifies information metadata, auxiliary fields, SAM interoperability, protection metadata and programming interfaces of genomic information. It defines: - metadata storage and interpretation for the different encapsulation levels as specified in ISO/IEC 23092-1 (in Clause 6); - protection elements providing confidentiality, integrity and privacy rules at the different encapsulation levels specified in ISO/IEC 23092-1 (in Clause 7); - how to associate auxiliary fields to encoded reads (in Clause 8); - mechanisms for backward compatibility with existing SAM content, and exportation to this format (in Annex C); - interfaces to access genomic information coded in compliance with ISO/IEC 23092-1 and ISO/IEC 23092-2 (in subclause 8.1).

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